KofamKOALA: KEGG Ortholog assignment based on profile HMM and adaptive score threshold
نویسندگان
چکیده
منابع مشابه
Automatic generation of KEGG OC (Ortholog Cluster) and its assignment to draft genomes
As the number of sequenced genomes are rapidly growing, a method for automatic generation of orthologous gene clusters is needed. However, it is computationally hard to cluster a large number of genes at once. To address this problem, we have developed a heuristic method to assign gene groups from closely related organisms to an ortholog cluster in a bottom-up approach. In this method, we consi...
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The identification of orthologous genes in an increasing number of fully sequenced genomes is a challenging issue in recent genome science. Here we present KEGG OC (http://www.genome.jp/tools/oc/), a novel database of ortholog clusters (OCs). The current version of KEGG OC contains 1 176 030 OCs, obtained by clustering 8 357 175 genes in 2112 complete genomes (153 eukaryotes, 1830 bacteria and ...
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ژورنال
عنوان ژورنال: Bioinformatics
سال: 2019
ISSN: 1367-4803,1460-2059
DOI: 10.1093/bioinformatics/btz859